Multiple Sclerosis Research Repository

1. “Selective caudate atrophy in multiple sclerosis: a 3D MRI parcellation study”: Bermel RA et al

-normalized bicaudate volume was 19% lower in MS than controls, an effect that persisted after adjusting for whole brain atrophy

-caudate volume did not correlate with disease duration, physical disability score, whole-brain atrophy or total T2 hyperintense or T1 hypointense lesion load

-selective caudate atrophy is associated with MS and may occur through direct mechanisms