Multiple Sclerosis Research Repository

 “Retinal imaging with optical coherence tomography: a biomarker in multiple sclerosis?”: Fiona Costello

-Recent reports have also suggested that OCT-measured microcystic macular edema and associated thickening of the retinal inner nuclear layer represent markers of active CNS inflammatory activity.

-OCT-detected decrements in retinal nerve fiber layer thickness and ganglion-cell layer–inner plexiform layer thickness, which represent markers of axonal damage and neuronal injury, respectively, have been shown to correlate with worse visual outcomes, increased clinical disability, and magnetic resonance imaging-measured burden of disease in MS patients.