Multiple Sclerosis Research Repository

1. “HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course”: L F Barcellos et al

-HLA-DRB*1501 allele and its associated haplotype (DRB1*1501-DQB1*0602 or DR2)

-we report that DF2 haplotypes modify disease progression

-there is a paucity of benign MS and an increase of severe MS in individuals homozygous for DR2