Multiple Sclerosis Research Repository

1.  “Clinical Outcomes of Escalation vs Early Intensive Disease-Modifying Therapy in Patients With Multiple Sclerosis”: Katharine Harding et al

-In this cohort study including 592 people, those who received high-efficacy treatment initially had a smaller increase in Expanded Disability Status Scale score at 5 years vs those who first received moderate-efficacy disease-modifying therapy.

-These findings suggest that real-world escalation approaches may be inadequate to prevent unfavorable long-term outcomes