Multiple Sclerosis Research Repository

1. “Changes in disability in people with multiple sclerosis: a 10-year prospective study” by David Conradsson et al

-The large proportion of our sample receiving immunomodulatory treatment at baseline needs to be taken into account when interpreting the study results.  The increase in EDSS scores in our study was similar to previous -1year follow-ups, monitoring cohorts, where a low proportion received immunomodulatory treatment.  The similarities in disease progression between our cohort and previous cohort studies might indicate that changes in severity of MS, as measured with EDSS, occur regardless of immunomodulatory treatment.